I spin up a lot of Vagrant boxes in /tmp for quick tests. Those tend to disappear before they’re properly cleaned up. Run this every once in a while to clear out Vagrant’s cache:
$ vagrant global-status --prune
Another, more tedious task is clearing out old boxes. This can recover quite a bit of disk space.
$ vagrant box list
$ vagrant box remove ubuntu/trusty32 --box-version 20150908.0.0
The box-version flag is necessary when a box has more than one version isntalled. The version string is the last value in parentheses listed by vagrant box list.